Betamethasone Basic information | |
Product Name: | Betamethasone |
Synonyms: | (8 s, 9 r, 10 s and 11 s, 13, 14, 16 s, r) 17-9 – fluoro – 11 – dihydroxy 12-17 – (2 – hydroxyacetyl) – 10,13,16 – trimethyl – 6,7,8,9,10,11,12,13,14, 15,16,17 – dodecahydro – 3 h – cyclopenta [a] phenanthren – 3 – one; BetamethasoneBase&Salts; Betamethasone, alpha – Fluoro – 11 beta 9, 17 alpha, 21 – trihydroxy – 16 beta methylpregna – 1, 4 – diene – 3, 20 – dione, 9 alpha – Fluoro – 16 beta – methyl – 11 beta, alpha, 21 – trih Ydroxy – 1, 4 – pregnadiene – 3, 20 – dione, 9 alpha Fluoro – 16 beta methylprednisolone; Betamethasone(200mg); BetaMethasone(Celestone) |
CAS: | 378-44-9 |
MF: | C47H51NO14 |
MW: | 853.92 |
EINECS: | 608-826-9 |
Product Categories: | Forensic and veterinary standards; Pharmaceutical raw materials; Corticosteroids; Food additives; Small molecule inhibitor; Nonsteroidal; Compound; Pharmaceutical anti-inflammatory drugs; The reagent; Cortical hormone; Steroid hormones (hormones, glucocorticoids); Hormones and drugs regulating endocrine function; Adrenocortical hormones; Raw materials for skin application; Agricultural raw materials; Skin steroid hormones; Anti-inflammatory analgesics; Pharmaceutical, pesticide and dye intermediates; Hormone regulatory class; Daily chemicals; Chemical raw materials; Chemical reagent |
Introduction | Betamethasone, also known as betamethasone, besocortol, betamethasone, and betamethasone, belongs to the adrenocortical hormone drugs, which has various pharmacological effects such as anti-inflammatory, anti-rheumatic, anti-allergic and immunosuppressive.
White crystalline powder. Odourless. |
Application | Hormone drugs. Mainly used for anti-inflammatory and anti-allergic. It is suitable for rheumatoid arthritis and various skin diseases. The effect of betamethasone is the same as that of dexamethasone, and its anti-inflammatory effect is stronger than that of dexamethasone, dexamethasone and hydrocortisone, with fewer side effects. |
Betamethasone Chemical Properties | |
Melting point | 235-237°C |
Boiling point | 568.2±50.0 °C(Predicted) |
Density | 1.1283 (estimate) |
flash point | 9℃ |
specific rotation | D +108° (acetone) |
Refractive index | 118 ° (C=1, Dioxane) |
Storage condition | 0-6°C |
Solubility | Practically insoluble in water, sparingly soluble in anhydrous ethanol, very slightly soluble in methylene chloride. |
form | Powder. |
color | White crystalline |
pKa | 12.13±0.70(Predicted) |