| Pregabalin Basic information | |
| Product Name: | Pregabalin |
| Synonyms: | 3(S)-(AMINOMETHYL)-5-METHYLHEXANOIC ACID;Pregablin;3-(Aminomethyl)-5-methyl-hexanoic acid;PREDNISOLONESODIUMPHOSPHATE;(R)-Pregabalin;(S)-Pregabalin |
| CAS: | 148553-50-8 |
| MF: | C8H17NO2 |
| MW: | 159.23 |
| EINECS: | 604-639-1 |
| Product Categories: | Pharmaceutical raw materials; Nervous system medication; Food additives; The spirit of class; Small molecule inhibitor; Ion channel; Plasma membrane; Antiepileptic; Chemical raw materials; Imported raw materials |
| Introduction | Pregabalin is a non-gamma-aminobutyrate (GABA) receptor agonist or antagonist. It is a new calcium channel regulator, which can block voltage-dependent calcium channels and reduce the release of neurotransmitters. |
| Application | Clinically, it is mainly used for neuralgia related to diabetic peripheral neuropathy, postherpetic neuralgia and adjunctive treatment of partial seizures in adults, generalized anxiety disorder, central neuralgia (including neuralgia associated with spinal cord injury, stroke and multiple sclerosis) and fibromyalgia. |
| Pregabalin Chemical Properties | |
| Melting point | 194-196°C |
| specific rotation | D23 +10.52° (c = 1.06 in water) |
| Boiling point | 274.0±23.0 °C(Predicted) |
| density | 0.997±0.06 g/cm3(Predicted) |
| flash point | 9℃ |
| storage temp. | 2-8°C |
| solubility | deionized water: ≥10mg/mL |
| form | Powder |
| color | White crystal powder or white fine crystal powder |
| pKa | 4.23±0.10(Predicted) |
